Medtox
Synonyms
Hippuric Acid; Methylhippuric Acid
Test Includes
Creatinine; Hippuric acid, g/L; Hippuric acid, g/g creatinine; Methylhippuric acid, g/L; Methylhippuric acid, g/g creatinine
Expected Turnaround Time
7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
In-house validated method
Specimen Requirements
Specimen
Urine (random)
Volume
10 mL
Minimum Volume
0.5 mL
Container
Plastic urine container or transport tube without preservative
Collection
Collection time: End of shift
Storage Instructions
Submission/transport (<3 days): Refrigerate. For storage beyond three days, specimen should be frozen.
Test Details
Use
Evaluate exposure to toluene, benzyl alcohol, or xylene
Methodology
Gas chromatography/flame ionization detection (GC/FID); Spectrophotometry (SPEC)
Reference Interval
Hippuric Acid: Normal (unexposed population): average 0.8 g/L; Exposed: Biological Exposure Index (BEI): 1.5 g/g creatinine (toluene exposure; end of shift); Toxic: not established; Methylhippuric Acid: Normal (unexposed population): none detected; Exposed: Biological Exposure Index (BEI): 1.5 g/g creatinine (end of shift), Biological Tolerance Value (BAT): 2.0 g/L (end of exposure or end of shift); Toxic: not established