Buprenorphine, whole blood

CPT: 80299

Synonyms

Subutex®; Buprenex®; Suboxone®


Test Includes

Buprenorphine; Norbuprenorphine


Expected Turnaround Time

7 - 10 days


Related Information

In-house validated method


Specimen Requirements


Specimen

Whole blood


Volume

3 mL


Minimum Volume

0.3 mL


Container

Gray-top (NaF/oxalate) tube, green-top (heparin) tube, or lavender-top (EDTA) tube


Collection

Trough levels are most reproducible


Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.


Test Details


Use

Therapeutic Drug Management


Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Reference Interval

Buprenorphine: 1.00 - 10.00 ng/mL; Norbuprenorphine: Not established