Opiates, unconjugated, serum or plasma

CPT: 80356;80361;80365

Test Includes

Codeine; Morphine; 6-Acetylmorphine (6-AM); Hydrocodone; Hydromorphone; Dihydrocodeine; Oxycodone; Oxymorphone

Expected Turnaround Time

5 days

Related Information

In-house validated method

Specimen Requirements


Specimen

Serum or plasma

Volume

10 mL

Minimum Volume

2 mL

Container

Red-top (no additive) tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Collection

Transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Test Details


Use

Detect use of opiate class drugs

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference Interval

Codeine: 10 - 100 ng/mL; Morphine: 21 - 65 ng/mL; Hydrocodone: 10 - 100 ng/mL; Hydromorphone: 1 - 30 ng/mL; Dihydrocodeine: Not established; Oxycodone: 10 - 100 ng/mL; Oxymorphone: 1 - 8 ng/mL