o,m,p-Xylene, Occupational Exposure, whole blood

CPT: 84600

Synonyms

Xylene

Expected Turnaround Time

7 days

Related Information

In-house validated method

Specimen Requirements


Specimen

Whole blood, heparinized

Volume

20 mL

Minimum Volume

7 mL

Container

Green-top (heparin) tube

Collection

Collect a minimum of two tubes; tubes should be filled to prevent loss of volatile into headspace. Collection time: End of shift or end of exposure

Storage Instructions

Submission/transport (<3 days): Refrigerate. For storage beyond three days, specimen should be frozen.

Test Details


Use

Evaluate exposure to o,m,p-xylene

Methodology

Headspace gas chromatography/flame ionization detection (GC/FID)

Reference Interval

Normal (unexposed population): none detected; Exposed: Biological Tolerance Value (BAT): 1.5 mg/L (end of exposure or end of shift); 1.0 mg/L xylenes resulted from air exposure to 100 ppm. Xylene exposure levels of 200 ppm correlated with onset of clinical effects including mucous membrane irritation, nausea, vomiting, dizziness, and incoordination; Toxic: not established