Gamma-Hydroxybutyric Acid (GHB), serum or plasma

CPT: 80307

Synonyms

GHB; γ-hydroxybutyrate

Expected Turnaround Time

5 days

Related Information

In-house validated method

Specimen Requirements


Specimen

Serum or plasma

Volume

5 mL

Minimum Volume

1.2 mL

Container

Red-top (no additive) tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Collection

Transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Test Details


Use

Detect use of gamma-hydroxybutyric acid (GHB), a psychoactive drug

Methodology

Initial presumptive testing by chromatography/tandem mass spectrometry (LC/MS-MS) at a testing threshold of 10.0 μg/mL; presumptive positives confirmed by definitive chromatography/mass spectrometry (GC/MS) at a testing threshold of 10.0 μg/mL

Reference Interval

NEGATIVE