Risperidone and 9-Hydroxyrisperidone, serum or plasma

CPT: 80342

Synonyms

Risperdal®


Expected Turnaround Time

5 - 7 days


Related Information

In-house validated method


Specimen Requirements


Specimen

Serum or plasma


Volume

3 mL


Minimum Volume

0.6 mL


Container

Red-top (no additive) tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.


Collection

Transfer separated serum or plasma to a plastic transport tube. Trough levels are most reproducible


Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.


Test Details


Use

Therapeutic Drug Management


Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Reference Interval

Expected steady state concentrations of risperidone and 9-hydroxyrisperidone (combined total) in patients receiving recommended daily dosages: 10 - 120 ng/mL