Medtox
Styrene (as Mandelic Acid and Phenylglyoxylic Acid), Occupational Exposure, urine
TEST:
71247
Test number copied
CPT:
83921;82570
Synonyms
Ethenylbenzene; Vinylbenzene
Test Includes
Creatinine; Mandelic Acid, mg/L; Mandelic Acid, mg/g creatinine; Phenylglyoxylic Acid, mg/L; Phenylglyoxylic Acid, mg/g creatinine; Mandelic & Phenylglyoxylic Acids, mg/L
Expected Turnaround Time
7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
In-house validated method
Specimen Requirements
Specimen
Urine (random)
Volume
10 mL
Minimum Volume
0.5 mL
Container
Plastic urine container or transport tube without preservative
Collection
Collection time: End of shift or end of exposure, prior to next shift
Storage Instructions
Submission/transport (<3 days): Refrigerate. For storage beyond three days, specimen should be frozen.
Test Details
Use
Evaluate exposure to styrene
Methodology
Gas chromatography/flame ionization detection (GC/FID); Spectrophotometry (SPEC)
Reference Interval
Mandelic Acid: Normal (unexposed population): endogenous levels up to 5 mg/L; Exposed: Biological Exposure Index (BEI): 800 mg/g creatinine (end of shift), 300 mg/g creatinine (prior to next shift); Toxic: Central nervous depression induced by styrene has been correlated with urine mandelic acid levels of 800 mg/L, decrements in psychomotor performance at >1200 mg/L. Phenylglyoxylic Acid: Normal (unexposed population): none detected; Exposed: Biological Exposure Index (BEI): 240 mg/g creatinine (end of shift), 100 mg/g creatinine (prior to next shift); Toxic: not established.